| 名稱 | ERBB2 p.V842I Reference Standard 標(biāo)準(zhǔn)品 |
| 型號(hào) | CBP10271 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | ERBB2 p.V842I Reference Standard |
產(chǎn)品搜索
相關(guān)文章
- STR標(biāo)準(zhǔn)品上新
- 腫瘤細(xì)胞與正常細(xì)胞的幾大區(qū)別總結(jié)
- 上海細(xì)胞庫(kù)——南京科佰生物
- 官宣！Ba/F3激酶穩(wěn)定細(xì)胞株&科佰激酶篩選平臺(tái)
- A2A受體家族細(xì)胞篩選模型
- Nectin-4, ADC賽道新星靶點(diǎn)
- 老靶點(diǎn)迭代突破創(chuàng)新：Her2靶點(diǎn)細(xì)胞模型
- 北京細(xì)胞庫(kù)關(guān)于細(xì)胞存儲(chǔ)的意義了解下
- MTHFR基因多態(tài)性用藥指導(dǎo)標(biāo)準(zhǔn)品
- HRD檢測(cè)之我見---科佰生物
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10271ERBB2 p.V842I Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
" _ue_custom_node_="true">
CBP10271 | |
| Format | Genomic DNA |
| Description | ERBB2 (HER2) V842I lies within the protein kinase domain of the Erbb2 (Her2) protein (UniProt.org). V842I results in increased Erbb2 (Her2) activity, downstream Mapk pathway activation, and the ability to transform cells in culture (PMID: 23220880), however in another study, V842I results in similar cell proliferation and viability levels as wild-type Erbb2 (Her2), in two different cell lines (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.2524G>A |
| AA Change | p.V842I |
| Mutation type | Substitution - Missense |
| Zygosity | Heterozygous |
| Allelic Frequency | 50.00% |
| Transcript | ENST00000269571 |
| Cosmic ID | COSM14065 |
| Chr position(GRCh37) | chr17:37881332 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
會(huì)員_a.png)