| 名稱(chēng) | BCR-ABL1 Q252H/T315I /BaF3 |
| 型號(hào) | CBP73278 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | BCR-ABL1 [Q252H/T315I] /BaF3,母細(xì)胞：BaF3，凍存條件：90% FBS+10% DMSO； |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
- 重磅！科學(xué)家成功利用免疫細(xì)胞運(yùn)輸抗癌藥物至腫瘤靶點(diǎn)
- 【連載-企業(yè)參考品】 前列腺癌的診斷參考品的選擇
- 3年回顧，賀教授敲錯(cuò)了基因？CXCR4 or CCR5
- 【產(chǎn)品推介】T細(xì)胞活化篩選模型
- 能量平衡的重要靶點(diǎn)——CRF1R和CRF2R
- 神舟十一號(hào)成功發(fā)射！哪些生物實(shí)驗(yàn)跟著上天了？
- 【新品上線】一種安全高效的中和抗體體外篩選模型
- 基于納米顆粒的組合免疫療法對(duì)致命性癌癥發(fā)起三重打擊
- JAK2激酶抑制劑細(xì)胞篩選模型
- 【產(chǎn)品推介】VEGFR-2（KDR）小分子抑制劑細(xì)胞篩選模型
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73278BCR-ABL1 Q252H/T315I /BaF3
- 詳細(xì)內(nèi)容
| CBP73278 | |
| I. Introduction | |
Cell Line Name： | BCR-ABL1 [Q252H/T315I] /BaF3 |
Host Cell: | Ba/F3 |
| Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
| II.Background | |
ABL1, ABL proto-oncogene 1, non-receptor tyrosine kinase, plays a role in regulation of cell growth through ERK5, Rac/JNK, and Stat1/3 pathways (PMID: 10373409). Fusion proteins of BCR-ABL1 resulting in constitutive kinase activity have been reported in various cancers (PMID: 18851712, PMID: 30125955) and a number of Abl1 mutations in the context of BCR-ABL1 have been demonstrated to confer drug resistance (PMID: 24456693). | |
| III. Representative Data | |
1.WB of BCR-ABL1 [Q252H/T315I] /BaF3
| |
2. Sanger of BCR-ABL1 [Q252H/T315I] /BaF3
Figure 2. BCR-ABL1 [Q252H/T315I] /BaF3 Fusion
Figure 3. BCR-ABL1 [Q252H/T315I] /BaF3 Q252H Mutation
Figure 4. BCR-ABL1 [Q252H/T315I] /BaF3 T315I Mutation | |
3. Anti-proliferation assay
Figure 5 .CTG Proliferation Assay of BaF3 BCR-ABL1 T315I Q252H Cells (C1). | |
會(huì)員_a.png)